Frequently Asked Questions

With standard shipping, orders within the US require 7-10 days.

If you are unsatisfied with your product purchase for any reason, you may return the product within 30 days for a full refund. Read about our return policy.

All ScienceBased Health products are gluten free. Our products do not contain wheat, rye, barley or oats - and do not contain ingredients derived from these grains. ScienceBased Health products should be appropriate for those with celiac disease or gluten sensitivities. However, anyone with a medical condition should always consult a doctor about what's best for them.

Use of multivitamin supplements was found to be unrelated to overall risk of prostate cancer in a recent prospective study. The study's authors did report, however, that a sub-group of men who used multi-vitamin and mineral supplements excessively (defined as more than 7 times a week) had an increased risk of advanced and fatal prostate cancer compared to men who never used multi-vitamins. However, significant questions remain about the way the study was designed and it's conclusions may not be applicable to the general public.

• The study classified multivitamin use among some participants as "excessive" - but this classification would be impossible to determine based solely on the survey questions used in the study. The reason for this discrepancy remain unknown.
• Men using multivitamins "excessively" were more likely to take a variety of individual supplements, making it impossible to identify or quantify any individual nutrients within the "multis" that could have been responsible for the observed association.
• It's well recognized that men at high risk for advanced prostate cancer or diagnosed with the disease, tend to use more alternative therapies including supplements (and it's conceivable therefore that some may also be more likely to exceed appropriate levels or to use supplements with questionable ingredients).
• In contrast, a follow-up analysis of the Age-Related Eye Disease Study (AREDS) found that AREDS participants taking zinc alone or with antioxidants were less likely to die after supplementation compared to those taking a placebo. No increased deaths from cancer in those taking zinc (alone or with anti-oxidants) was noted in this analysis. AREDS used a "gold standard" study method; it was a placebo-controlled, double-blind intervention study. This type of study is known to be more reliable than prospective studies like the one in question, which rely on participant's answers to a survey.

However, to err on the side of safety, men with elevated PSA levels or diagnosed with prostate cancer should discuss the issue with their own physician to determine the best course of action. Even though the findings of this study have been questioned, the study points up some common sense practices worthy of emphasis:

• Don't use daily multi-vitamins excessively. Use them as directed. The idea that "if a little is good, more is better" is not always the best recipe for good health.
  
• As a general rule, don't combine many individual nutrient supplements instead of a taking a multi - or even in addition to a multi - unless advised to do so by a qualified health professional. Each individual nutrient has its own unique safety range, and taking many nutrients singly, or in addition to a multi, could result in exceeding those safety ranges.
• Choose multis that are formulated by nutrition scientists and ocular experts to ensure that supplements contain the highest quality ingredients, are balanced and scientifically sound.

Read more about this study

ScienceBased Health has joined experts in questioning the validity of the conclusions drawn by Johns Hopkins researchers regarding vitamin E use and increased mortality risk. A number of experts - from those who evaluate vitamin safety to statisticians at Harvard and UC Berkeley - are not convinced about the conclusions reached from a meta-analysis that 400 IU of vitamin E could be harmful. The study, widely criticized as flawed, found only a tiny adverse effect - less than ½ of one percent - and the New York Times reported that some prominent statisticians found the analysis to be unpersuasive. Read More

“Daily Value (DV)” is a term used and set by the FDA. It replaced the FDA's term “US RDA”. The terminology change was the result of finalization of the labeling regulations portion of DSHEA (Dietary Supplement Health and Education Act) that mandated using the Supplement Facts Box on supplement labels.

The DVs are the FDA’s version of the Institute of Medicine's recommended intakes for vitamins and minerals. The Institute of Medicine and its Food and Nutrition Board are part of the National Academy of Sciences.

The Institute of Medicine sets levels of RDAs (Recommended Dietary Allowances) for vitamins and minerals that are broken down by age and gender. These RDAs are generally lower than DVs and are used by the Federal government for planning of food programs like school lunches, etc.

The Institute of Medicine has been releasing new reports called Dietary Reference Intakes (DRIs). The report sets recommended dietary allowance (RDA), adequate intake (AI) and upper intake levels (UL) for vitamins and minerals. So far the FDA has not revised the Daily Values to reflect any of these changes, and it is the DVs only that are used on supplement labels and of which consumers need be aware.

The FDA neither approves or disapproves of dietary supplements, as it does for drugs. This is because dietary supplements have been determined to be safe within a broad range of intake and safety problems with supplements are relatively rare. Dietary supplements are regulated only for labeling and advertising by the FDA (within the US Department of Health and Human Services) under a federal statute passed in 1994 called DSHEA (the Dietary Supplement Health and Education Act). All ingredients used in ScienceBased Health’s products have a long history of safe use.

All ScienceBased Health products are manufactured in strict adherence to cGMP's (Current Good Manufacturing Principles) and rigorous internal protocol. They are certified Kosher by an independent company. Every batch of each ScienceBased Health product is accompanied by a certificate of analysis to ensure that potency meets stated label claim of potency. Additionally, ScienceBased Health conducts routine, independent testing on product ingredients to ensure bottle contents are consistent with label claims. ScienceBased Health uses the highest quality raw materials, including pharmaceutical grade components wherever available.

Purified lutein, such as FloraGLO®, used in ScienceBased Health products is considered a superior source for the following reasons: 1) lutein is the predominate form in foods, making up 80% while lutein esters makes up only 6%; and 2) lutein may be more easily or readily absorbed than ester forms, because the fatty acids that comprise the "ester" have to be removed by enzymes before absorption can take place. The absorption of lutein from lutein esters is also less efficient when taken with a low-fat meal.

Read an interview with ScienceBased Health Science Advisory Board Member, Paul S. Bernstein, MD, PhD, on the role of lutein in macular health. Listen to the audio version!

While a recent study (The Nurse’s Health Study) published in the Journal of the American Medical Association (JAMA) implies that vitamin A intake causes fractures in women, this study is contradicted by other powerful studies that did not find this correlation. Additionally, the Institute of Medicine (IOM) recently set a safe Upper Level (UL) on retinol (preformed) vitamin A of 10,000 IU (3000 RE), the amount considered safe for virtually all the population. The Council for Responsible Nutrition (CRN), in consultation with independent osteoporosis and vitamin A experts, reaffirmed that the current UL for vitamin A set by the Institute of Medicine (IOM) is appropriate, even after reviewing these study results. It is important to keep in mind that the Nurse’s Health Study is referred to as "observational", a study which can only show an association or link between a behavior and an outcome. It does not offer proof of cause and effect, nor does it rule out that the findings may be due to other factors.

All ScienceBased Health formulations fall well within the safe UL for vitamin A intake, even when combined with the typical dietary intakes.

DiaVis is a specialized oral formulation designed to provide nutritional support for those with diabetes mellitus or those highly at risk for this condition. It offers a unique blend of antioxidants and other key nutrients to help protect vision and promote overall health. DiaVis provides tailored support in two capsules daily.

Observational and clinical studies have identified nutrients that may be low in diabetics due to altered requirements, inadequate intake, increased excretion or higher oxidative stress. Diabetics are at increased risk for vision loss, and oxidative stress is one contributing factor. DiaVis delivers nutrients that:

• help combat oxidative stress and inflammation
• can be marginally deficient and that play a role in normal glucose metabolism
• may be affected by the use of diabetes-related medications
• support retinal vessel health
• promote a healthy equilibrium of fluids in the eye
• are associated with a reduced risk of developing diabetes

DiaVis is appropriate for use by adult men and women with, or at risk for:

• type 1 or 2 diabetes
• diabetes-related changes in retinal health
• pre-diabetes or impaired glucose tolerance

It is highly recommended that DiaVis be taken in conjunction with ScienceBased Health’s OmegaAdvance®, a pharmaceutical grade fish oil supplement that provides a concentrated source of the omega-3 fats EPA and DHA, along with lutein and olive leaf extract. The ingredients in OmegaAdvance complement DiaVis by helping to guard against factors involved in detrimental changes to the retina’s vessels and nerve cells. These factors include ischemia (inadequate blood supply), damage from light exposure, free radicals, inflammation and age-related retinal changes.

• EPA and DHA may act against retinal vessel loss, growth of abnormal vessels, and inflammation
• EPA and DHA offer well recognized support for cardiovascular health
• Lutein has demonstrated anti-inflammatory properties, while the unique compounds in olive leaf extract act as potent antioxidants

• Yes, though as with any dietary supplement, patients with medical conditions and/or using prescription medications should inform their primary care doctor when adding DiaVis to their daily regimen.
• While potential interactions between medications and DiaVis ingredients appear to be minimal, routine monitoring is prudent. An interaction chart provides information about potential interactions of DiaVis ingredients with common anti-diabetic medications and tests, and takes into account other drugs used to prevent or treat diabetic complications such as cardiovascular, kidney, eye and peripheral nerve disease.
• Some diabetes-related medications can also interfere with metabolism of certain nutrients, which may need to be supplemented. These ingredients are included in DiaVis, and are also identified within the chart.

HydroEye offers long-lasting effectiveness with continued use. Results are typically experienced within 30-60 days.

HydroEye is an oral formulation that works from the inside out to target the root causes of dry eye. Unlike topical products like drops and artificial tears, HydroEye does not require frequent re-application throughout the day. HydroEye provides uninterrupted relief within 30-60 days.

HydroEye may be combined with artificial tears, punctum plugs or the medication Restasis®. Because HydroEye is an oral formulation that targets dry eye internally, it works by a complementary mode of action to these topical products. However, most users find that HydroEye provides adequate relief within 30-60 days.

A study published in 1994 reported that supplemental GLA lowered triglycerides, increased levels of "good" HDL cholesterol and prolonged the time it takes for blood platelets to clump together- factors which may contribute to cardiovascular health.

Platelets in the blood have a sticky surface which allows them, along with other substances, to form blood clots when bleeding occurs, a process called coagulation. Since platelets are involved in the process of forming clots, the GLA contained in HydroEye could theoretically increase the effects of anti-coagulant and anti-platelet medications such as Coumadin, Plavix or aspirin. If you are taking "blood thinning" medications, your physician can perform a Prothrombin time, INR, or bleeding time test to measure how long it takes blood to clot. This will ensure that HydroEye can safely be added to your current drug regimen.

HydroEye provides the same omega-3s as flaxseed and fish oil. HydroEye now features EPA and DHA from highest-quality, USP verified fish oil. However, only HydroEye provides GLA (gamma linolenic acid). GLA effectively promotes the body's production of anti-inflammatory compounds. Both GLA and the omega-3 from fish oils have anti-inflammatory actions, but only GLA has been clinically shown to decrease dry eye symptoms.

Additionally, neither fish nor flaxseed oils contain other important nutrients that are included in HydroEye: vitamin B6 and magnesium to promote fatty acid metabolism, vitamin A to support the production of mucin in the tear film, and the antioxidant vitamin C to help fight the free radicals associated with inflammation.

Research suggests that the EE (Ethyl Ester) and TG (triglyceride) forms of omega fatty acids from fish oil are absorbed about the same when taken over several weeks or more. While some research measuring absorption over just a single day or less found the TG form to be better absorbed, differences disappear in studies that compared these forms over two weeks or more. SBH products contain the EE form, as the EE form has been used in nearly every clinical trial showing benefit for omega-3s from fish oil and is the choice for the National Eye Institute’s AREDS 2 trial now in progress. Learn more

Although discussion of fish omega forms has centered on their use for dry eye, research has not yet shown fish omegas to be a lead dry eye player. Instead, they are a useful adjunct to GLA, an omega that has demonstrated significant dry eye benefit in three clinical trials. When the fish omega EPA is paired with GLA, they reduce inflammation in a complementary fashion. HydroEye features GLA plus USP-verified fish oil that, along with other important nutrients, fights inflammation and supports all three layers of the tear film.

PCBs are chemicals known as polychlorinated biphenyls. They are man-made, accumulate in the food chain, and are associated with cancer and birth defects.

ScienceBased Health's supplier of omega-3 fish oil removes the impurities found in fish oils (such as PCBs and mercury) before the fish oil is concentrated. The processing it undergoes also removes other contaminants such as dioxin and furans (toxic chemicals that have been associated with a wide range of adverse health effects). Further, every batch of fish oil is routinely tested for these contaminants – and is always far below the “safe harbor, no significant risk level” limit set by Proposition 65.

Additionally, our supplier is the only producer of fish oil in the world to achieve the U.S. Pharmacopeia (USP) verification. USP is the body that establishes the quality standards for the FDA and all medicines in the US. USP verification means that the source of fish oils SBH uses has been prepared under accepted manufacturing practices to ensure consistent quality, and that the ingredients meet stringent purity requirements. Specifically, as part of verification, USP has tested for PCBs and found that this fish oil meets strict USP standards for contaminant levels.

ScienceBased Health uses USP-verified fish oil in its omega-3 fish oil product, OmegaAdvance – as well as in HydroEye and Optic Nerve Formula.

Sufficient scientific evidence for safe use of GLA during pregnancy and while breastfeeding is not available.

MacularProtect Complete-S is free of beta-carotene and intended for individuals, such as smokers, who should avoid high beta-carotene intake.

An additional multivitamin should not be used with MacularProtect Complete. MacularProtect Complete is a powerful formulation to protect macular health and also includes a complete multivitamin. The multivitamin component of MacularProtect Complete is robust, providing meaningful quantities of key nutrients at higher levels than are found in most daily multivitamins such as One-A-Day® or Centrum® Silver.

There are two very different types of vitamin A. The first, called preformed vitamin A, (usually listed on labels either as just "Vitamin A", or with the words "retinol" or "retinyl" in the name) should be used in moderate doses (we suggest less than about 5,000 IU per day from supplements).

The other type, used in AREDS and featured in MacularProtect Complete, is beta-carotene. Beta-carotene, although it’s listed on supplement labels as vitamin A by convention, must actually be converted into vitamin A in the body – and only on an as-needed basis, making it impossible to overdose on vitamin A from this source. Beta-carotene is considered safe at AREDS doses for most everyone except smokers and recent ex-smokers, who should be much more cautious with their intake. ScienceBased Health offers MacularProtect Complete-S which is beta-carotene free for those, like smokers, who should avoid high beta-carotene intake.

ScienceBased Health has joined experts in questioning the validity of the conclusions drawn by Johns Hopkins researchers regarding vitamin E use and increased mortality risk. A number of experts - from those who evaluate vitamin safety to statisticians at Harvard and UC Berkeley - are not convinced about the conclusions reached from a meta-analysis that 400 IU of vitamin E could be harmful. The study, widely criticized as flawed, found only a tiny adverse effect - less than ½ of one percent - and the New York Times reported that some prominent statisticians found the analysis to be unpersuasive.

MacularProtect Plus includes lutein rather than beta-carotene for two reasons. First, advanced scientific evidence points to lutein and zeaxanthin as the most important carotenoids in eye tissue. Secondly, there are potential safety concerns with the use of high dose beta carotene for some individuals.

The AREDS clinical trial was initiated in 1992. At that time, the AREDS investigators considered the carotenoids lutein and zeaxanthin to be potentially beneficial for macular health. However, they were unable to include these nutrients in the trial because they were not available in research-grade supplement form. Beta-carotene, another carotenoid with antioxidant potential, was included instead because it was readily available and was being studied in other trials for cancer and heart disease.

After AREDS began in 1992, several population-health studies found a relationship between higher lutein consumption and lower risk of AMD or cataract extraction that was not seen with beta-carotene. Lutein and zeaxanthin are the only carotenoids detected in the lens and macula of the eye, and several preliminary studies have indicated that high dose lutein (12 mg or greater) can increase macular pigment density. These findings point to the importance of lutein and zeaxanthin for maintaining eye health.

Two large scale studies, the CARET Study and the ATBC Cancer Prevention Trial, reported (after AREDS had started) that high dose beta-carotene increases the risk of lung cancer in smokers, ex-smokers and workers chronically exposed to asbestos. For this reason, high dose beta-carotene is best avoided by these people. Unfortunately, smoking also raises the risk of AMD. Additionally, AREDS participants who took antioxidants reported yellowing of the skin, a relatively harmless but visible side-effect of chronic high dose beta-carotene intake.

Vitamin A (also known as pre-formed A or retinyl palmitate) is essential for proper eye health. It protects against night-blindness and is vital for the health of the eye’s cornea. It also works with zinc to support the proper function of various eye structures.

While beta-carotene can also be converted to vitamin A, recent studies show that this beta carotene-conversion is far less efficient than once thought. For this reason, both vitamin A and beta-carotene are incuded in MacularProtect Plus.

Lutein and zeaxanthin are similar carotenoids that make up the pigment of the macula. A number of studies have shown an inverse association between macular pigment density and the risk of AMD. In other words, less density in the pigment of the macula increases AMD risk. Studies also indicate that the density of this pigment is linked to how much of these carotenoids we regularly consume.

To date, four published studies have found that increasing lutein through food sources or supplementation can actually improve macular pigment density. In these studies, the range of intakes - 10 mg to 30 mg - have been shown to improve density by 5 to 20-30%. Note that doses of approximately 12 and 20 mg reflect about the same 18-19% increase. Nor is the difference that great between that 19% and the 21%-39% improvement seen in only two test subjects given 30 mg daily. Given this research and the fact that the long-term effects of giving 30 mg of lutein are not known, ScienceBased Health determined that 15 mg was a prudent dose to deliver. These studies also reveal that changes in macular pigment can vary between individuals in response to lutein. A small number of people appear to be non-responders, for example, and women seem to channel some of the lutein consumed to body fat more readily than do men.

Read an interview with ScienceBased Health Science Advisory Board Member, Paul S. Bernstein, MD, PhD, on the role of lutein in macular health. Listen to the audio version!

Selenium is an essential trace element that must be obtained from foods. It is needed for the proper functioning of glutathione peroxidase, a key antioxidant enzyme present in eye tissues. As an integral part of this enzyme, selenium acts to inactivate damaging free radicals.

Selenium is also important for older men. It has been found in studies to help maintain prostate gland tissue. A large scale intervention trial by the NIH is now underway which will be examining the effects of vitamin E and selenium on prostate health.

Copper is an essential trace element that is needed for activating antioxidant enzymes and enzymes that help process amino acids. It is included in MacularProtect Plus to help keep a normal level of copper in the body. High dose zinc can decrease copper absorption, raising the risk of copper-deficiency anemia called (hypochromic microcytic anemia).

MacularProtect Plus is an effective stand-alone formulation for powerful macular protection. If you want to add whole body, multinutrient support, one-half daily dose (one capsule twice daily) of MacularProtect Plus may be safely combined with a full dose (two capsules twice daily) of OcularProtect. Another alternative is MacularProtect Complete, which combines protection for macular health with a complete multivitamin in a convenient all-in-one formulation.

Over two-thirds of the AREDS participants choose to take a one-a-day multi along with their study supplement. OcularProtect is an optimal choice as a companion multi, because it is more comprehensive than common multivitamins and is formulated to keep overall zinc intake at the level supplemented in the AREDS report.

ScienceBased Health has joined experts in questioning the validity of the conclusions drawn by Johns Hopkins researchers regarding vitamin E use and increased mortality risk. A number of experts - from those who evaluate vitamin safety to statisticians at Harvard and UC Berkeley - are not convinced about the conclusions reached from a meta-analysis that 400 IU of vitamin E could be harmful. The study, widely criticized as flawed, found only a tiny adverse effect - less than ½ of one percent - and the New York Times reported that some prominent statisticians found the analysis to be unpersuasive. Read More

OcularProtect provides higher levels of key nutrients, consistent with research findings, than other products on the market. For instance, compared to Centrum Silver:

• OcularProtect provides 28 times the amount of lutein.
• OcularProtect provides over 6 times the amount of vitamin C.
• OcularProtect provides over 4 times the amount of vitamin E, as natural mixed tocopherols and natural source d-alpha-tocopheryl succinate.
• OcularProtect provides alpha lipoic acid and an array of flavonoids, such as Ginkgo biloba, grape seed, citrus, quercetin and bilberry, from diverse sources. Lipoic acid and flavonoids are not present in Centrum Silver.
• OcularProtect provides over 2.5 times the amount of zinc.
• OcularProtect is in capsule form - rather than tablet - for efficient dissolution and is free of artificial colors and preservatives.
• OcularProtect features potent cell-protecting ingredients: green tea extract, broccoli sprout extract and OptiBerry® Mixed Berry Blend.

View a comparison chart of OcularProtect with other multis & ocular products

• A unique omega-3 fish oil supplement with lutein & olive leaf extract

• 2 softgels contain:
  • 500 mg omega-3 (300 mg EPA , 200 mg DHA )
  • 1.5 mg lutein (plus 32 mcg zeaxanthin)
  • 25 mg olive leaf extract (18% oleuropein)
  • 3 IU vitamin E (d-alpha tocopherol, natural)

• The scientific support is strong that regular omega-3 intake lowers risk of heart disease; support for visual health is growing
  • Studies link greater intake or higher blood levels of EPA /DHA with lower risk of AMD
  • Most people do not obtain enough omega-3 from their diet and/or are concerned about contaminants in fatty fish: typical intake is 100 mg EPA /DHA daily, while 400-600 mg is advised

Research suggests that the EE (Ethyl Ester) and TG (triglyceride) forms of omega fatty acids from fish oil are absorbed about the same when taken over several weeks or more. While some research measuring absorption over just a single day or less found the TG form to be better absorbed, differences disappear in studies that compared these forms over two weeks or more. SBH products contain the EE form, as the EE form has been used in nearly every clinical trial showing benefit for omega-3s from fish oil and is the choice for the National Eye Institute’s AREDS 2 trial now in progress. Learn more

• Target audience is wide, and encompasses those:
  • Concerned about their macular health
  • Wanting to support heart health
  • Wanting to help support normal blood sugar metabolism
  • Possibly those wanting to maintain cognitive health with age

• EPA and DHA are long-chain fatty acids found in fatty fish that play important roles in health
  • EPA helps maintain balance of pro- & anti-inflammatory compounds
  • DHA is the major structural fatty acid in retinal & brain cell membranes
  • EPA & DHA help keep cell membranes flexible for healthy function

• Research has shown that they:
  • Promote regular heart beat rhythm
  • Help maintain healthy triglyceride levels
  • May slow the growth rate of plaque in blood vessels
  • Promote a less “inflammatory” environment (inflammation is a factor in CVD & likely AMD as well)
  • Help protect photoreceptor cells (rods & cones)

• OmegaAdvance provides 500 mg of highly concentrated fish oil that yields 300 mg of EPA and 200 mg of DHA . Some products utilize a less concentrated form of fish oil, which means you need much more of it to obtain the same amount of EPA and DHA found in OmegaAdvance. For example, some products providing as much as 2,000 mg of fish oil yield the same amount of EPA and DHA contained in OmegaAdvance.
• Extremely Pure
  • Uses FIRST AND ONLY “pharmaceutical grade” fish oil ingredient to achieve US Pharmacopoeia (USP) verification – the most rigorous quality assurance verification in the world
  • Rigorously tested for heavy metals (including mercury and arsenic) and marine contaminants
  • Sourced from cold, pristine, deep waters off South America where there are significantly less environmental impurities
  • Undergoes multiple tests to ensure stability and molecular distillation, a purification process that concentrates omega-3s and helps eliminate contaminants
• Very concentrated
  • Most fish oil contains about 50% or less of omega-3; OmegaAdvance contains a minimum of 60% (35% EPA and 25% DHA )
• Provides 1.5 mg of lutein

  6 times the amount found in multivitamins such as Centrum Silver® and One-A-Day®

  Reflects pairing of lutein and omega-3 in the AREDS-2 trial (now in progress)

• Contributes the unique polyphenols found in olive leaf extract
  • Polyphenols are one of the key components of olive oil that research suggests may confer heart & blood vessel benefits
  • Unique polyphenols found in olive leaf extract act as potent antioxidants
  • Contains antioxidants for fish oil stability
• Meets omega-3 recommendations by AHA (American Heart Association)
• Natural lemon scent – no fishy odor
• Reasonably sized softgels
• Flexible daily dose to accommodate differences in fish intake
  • 2 softgels offer flexibility to consumers with different fish-consumption habits; those who eat cold water fish 1-2 times weekly can take 1 softgel daily

• Taking OmegaAdvance with anticoagulants (such as Coumadin): While the level of EPA /DHA in OmegaAdvance is unlikely to cause any increased bleeding problems in people taking those medications, it is best for those taking anticoagulants to check with their physician

PCBs are chemicals known as polychlorinated biphenyls. They are man-made, accumulate in the food chain, and are associated with cancer and birth defects.

ScienceBased Health's supplier of omega-3 fish oil removes the impurities found in fish oils (such as PCBs and mercury) before the fish oil is concentrated. The processing it undergoes also removes other contaminants such as dioxin and furans (toxic chemicals that have been associated with a wide range of adverse health effects). Further, every batch of fish oil is routinely tested for these contaminants – and is always far below the “safe harbor, no significant risk level” limit set by Proposition 65.

Additionally, our supplier is the only producer of fish oil in the world to achieve the U.S. Pharmacopeia (USP) verification. USP is the body that establishes the quality standards for the FDA and all medicines in the US. USP verification means that the source of fish oils SBH uses has been prepared under accepted manufacturing practices to ensure consistent quality, and that the ingredients meet stringent purity requirements. Specifically, as part of verification, USP has tested for PCBs and found that this fish oil meets strict USP standards for contaminant levels.

ScienceBased Health uses USP-verified fish oil in its omega-3 fish oil product, OmegaAdvance – as well as in HydroEye and Optic Nerve Formula.

Optic Nerve Formula is a specialized oral formulation designed to help protect the optic nerve. It provides targeted support in four softgels daily.

• Quench free radicals
• Enhance ocular circulation
• Promote normal vascular function.
• Inhibit compounds that damage nerve cells

• Those with optic nerve disorders
• Those wanting to help protect optic nerve health

Optic Nerve Formula can be appropriately used when intra-ocular pressure (IOP) is elevated as well as when IOP falls within the normal range. Glaucoma is now viewed as a neurodegenerative disease that occurs over a wide range of IOP. Oxidative stress plays a role in damage to neurons and cells in the trabecular meshwork, and ocular defenses may be compromised in glaucoma. Since glaucoma can progress despite treatment, Optic Nerve Formula can complement IOP lowering treatments for those with elevated or normal IOP.

The ingredient Ginkgo biloba may affect platelet aggregation. Thus, the use of Optic Nerve Formula along with anti-coagulation or anti-platelet medications could raise the risk of increased bleeding. This can be monitored by occasionally measuring Pro-thrombin Time and International Normalized Ratio (PT/INR) to evaluate the ability of the blood to clot properly. The formula is not intended for pregnant or lactating women. Individuals with an existing medical condition should consult their physician before using.

Adding a link to www.sciencebasedhealth.com from your website is simple. To do this, you will first need to speak with your web developer, website administrator, or webmaster. Ask them to create a hyperlink to www.sciencebasedhealth.com (or provide the full URL for a sub-page, such as the HydroEye page) and specify the location on your website where you would like it to appear.

There are many ways to display links. The following examples all contain text links to www.sciencebasedhealth.com:

• "Click here to view the www.sciencebasedhealth.com website"
• www.sciencebasedhealth.com
• "HydroEye is produced by ScienceBased Health"

In addition, images can also be linked (clicking on the image, when linked properly, would open www.sciencebasedhealth.com). Once again, ask the person in charge of your organization's website. As long as images are used to directly promote or educate about ScienceBased Health or its products, you may use any image (such as bottle photos, logos, promotional images) from the ScienceBased Health website on the website of a medical practice or organization*. To do this, simply right-click (Mac users: control-click) and select "copy", then right-click again on a folder on your computer and choose "paste" to paste the image onto your computer - then give this image to your web developer.

*All images and text on www.sciencebasedhealth.com are protected by copyright. Any use of images from www.sciencebasedhealth.com that does not directly promote ScienceBased Health or its products is strictly by permission only. Promotion of ScienceBased Health products for uses not explicitly mentioned on this website or in ScienceBased Health product materials, is strictly prohibited. ScienceBased Health is not responsible for how the company or its products are represented on websites other than www.sciencebasedhealth.com.